Digital Organism Simulation Environment (DOSE): A Library for Ecologically-Based In Silico Experimental Evolution

Clarence FG Castillo, Maurice HT Ling


Testing evolutionary hypothesis in biological setting is expensive and time consuming. Computer simulations of organisms (digital organisms) are commonly used proxies to study evolutionary processes. A number of digital organism simulators have been developed but are deficient in biological and ecological parallels. In this study, we present DOSE (Digital Organism Simulation Environment), a digital organism simulator with biological and ecological parallels. DOSE consists of a biological hierarchy of genetic sequences, organism, population, and ecosystem. A 3-character instruction set that does not take any operand is used as genetic code for digital organism, which the 3-nucleotide codon structure in naturally occurring DNA. The evolutionary driver is simulated by a genetic algorithm. We demonstrate the utility in examining the effects of migration on heterozygosity, also known as local genetic distance.


Digital Organisms; Simulation Environment; Ecology Simulation; Migration; Genetic Distance

Full Text:


Lululemon Black Friday cheap nfl jerseys Lululemon factory Outlet ny Black Friday discount tiffany outlet wholesale soccer jerseys online oakley black friday cheap nhl jerseys china cheap nfl jerseys north face black friday sale cheap nfl jerseys online Jordans Black Friday Sale 2015 Cheap Moncler Cyber Monday moncler outlet cheap soccer jerseys moncler outlet black friday cheap authentic nfl jerseys north face cyber monday Louboutin Black Friday canada wholesale cheap nfl jerseys lululemon cyber monday 2015 cheap nfl jerseys from china 2015 Cheap Moncler Black Friday Sale Moncler Cyber Monday 2015 cheap jerseys Lululemon Cyber Monday Sale jordans cyber monday deals 2015 cheap nike nfl jerseys Black Friday deals Lululemon 2015 jordan black friday 2015 Moncler Jackets Black Friday Sale 2015 Louboutin Pas Cher Black Friday 2015 Canada Lululemon north face black friday cheap wholesale soccer jerseys